Latest progress from PharmNovo at EFIC
PharmNovo will participate in the 13th Congress of the European Pain Federation, EFIC, in Budapest from 20-22 September. The EFIC Congress is the largest international congress on pain.
“We are very much looking forward to the congress and to describe our latest progress. PharmNovo is at the forefront of the field, pioneering the development of a delta opioid agonist. At this stage, we are more than ready to present our successful outcomes to the meeting, and to share these with our peers, investors, and collaborators”, says PharmNovo's Founder and Scientific Advisor, Bengt von Mentzer.
Bengt von Mentzer will be presenting two posters on PharmNovo's PN6047, our innovative drug candidate for neuropathic pain:
- Toxicity and safety testing of PN6047 – a delta agonist
In preclinical studies, PN6047 is shown to be safe and well tolerated with a wide estimated therapeutic window and lacking abuse potential. Preliminary results from the human phase I study show a similar profile and strongly indicate that PN6047 will be safe and tolerable and able to enter phase II efficacy studies in neuropathic pain patients.
- Antitussive activity of delta opioid receptor agonists
New data indicate that delta opioid agonists could provide a potential novel therapy for chronic cough without the unwanted effects, such as reduced respiration, of conventional non-selective opioids.
“Our successful phase I study was executed with professionalism and speed. We have now passed several important milestones and are well on our way in our mission to launch PN6047 as a compound for treating neuropathic pain and other conditions involving hypersensitivity in the nervous system. We are excited to enter the next, phase 2, stage of clinical testing with the potential of providing a new therapy to the millions of people suffering from neuropathic pain” says Bengt von Mentzer.
The European Pain Federation EFIC is a non-profit organisation representing healthcare professionals in pain management and science.
To learn more about the Congress of the European Pain Federation and to explore the agenda for the world congress, visit: https://europeanpainfederation.eu/efic2023/
Latest progress from PharmNovo at EFIC
PharmNovo will participate in the 13th Congress of the European Pain Federation, EFIC, in Budapest from 20-22 September. The EFIC Congress is the largest international congress on pain.
“We are very much looking forward to the congress and to describe our latest progress. PharmNovo is at the forefront of the field, pioneering the development of a delta opioid agonist. At this stage, we are more than ready to present our successful outcomes to the meeting, and to share these with our peers, investors, and collaborators”, says PharmNovo's Founder and Scientific Advisor, Bengt von Mentzer.
Bengt von Mentzer will be presenting two posters on PharmNovo's PN6047, our innovative drug candidate for neuropathic pain:
- Toxicity and safety testing of PN6047 – a delta agonist
In preclinical studies, PN6047 is shown to be safe and well tolerated with a wide estimated therapeutic window and lacking abuse potential. Preliminary results from the human phase I study show a similar profile and strongly indicate that PN6047 will be safe and tolerable and able to enter phase II efficacy studies in neuropathic pain patients.
- Antitussive activity of delta opioid receptor agonists
New data indicate that delta opioid agonists could provide a potential novel therapy for chronic cough without the unwanted effects, such as reduced respiration, of conventional non-selective opioids.
“Our successful phase I study was executed with professionalism and speed. We have now passed several important milestones and are well on our way in our mission to launch PN6047 as a compound for treating neuropathic pain and other conditions involving hypersensitivity in the nervous system. We are excited to enter the next, phase 2, stage of clinical testing with the potential of providing a new therapy to the millions of people suffering from neuropathic pain” says Bengt von Mentzer.
The European Pain Federation EFIC is a non-profit organisation representing healthcare professionals in pain management and science.
To learn more about the Congress of the European Pain Federation and to explore the agenda for the world congress, visit: https://europeanpainfederation.eu/efic2023/
Latest news
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Positive FDA feedback for PN6047
PharmNovo has received positive and constructive feedback from the FDA for its lead drug candidate, PN6047, a selective delta opioid receptor agonist aimed at treating peripheral neuropathy with allodynia. Following a successful pre-IND meeting in January 2025, the FDA provided valuable guidance on the Phase IIa study design and had no critical comments on the CMC or non-clinical data. This paves the way for IND submission by the end of 2025 and a Phase IIa clinical trial application in Europe (Spain, Poland, Czech Republic) by Q3 2025.
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Pioneering approach to treat neuropathic pain
PharmNovo has recently published an article in MedNous, highlighting the pioneering approach to tackling neuropathic pain without the risks traditionally associated with opioids. The lead candidate, PN6047, targets the delta-opioid receptor – offering pain relief without addiction or sedation. Arrangements for a Phase II trial have now been completed, marking a crucial step toward a safer alternative for millions suffering from chronic pain. With the opioid crisis still a major concern, innovative, non-addictive treatments like PN6047 are more urgent than ever.
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PharmNovo live at neurology theme event at RedEye
Per von Mentzer, CEO, presented PN6047 at the Neurology Event at RedEye on October 23. Take the opportunity to listen to a very interesting live presentation and learn more about PN6047, the unique first-in-class phase II ready asset with break-through potential in treatment of neuropathic pain. PN6047 demonstrates safety and tolerability and a lack of the adverse effects commonly associated with conventional opioids. These findings suggest a promising path forward in the field of pain management.
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PharmNovo at the LSX Nordic Congress
PharmNovo attended the LSX Nordic Congress in Copenhagen 8-9 October and Per von Mentzer, CEO presented PN6047, a unique first-in-class phase II ready asset with break-through potential in treatment of neuropathic pain. Being one of 68 companies that have recently been awarded by EIC for up to 17.5 MEUR (2.5 MEUR grant and up to 15 MEUR equity) from a total of 969 applicants is a strong validation of the potential of the phase II ready asset PN6047 and of PharmNovo. Take the opportunity to listen to the presentation here:
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